r-Sm14 - pRSETA efficacy in experimental animals

r-Sm14 - pRSETA efficacy in experimental animals.

Previous studies carried out with Sm14 in experimental vaccination against Schistosoma mansoni or Fasciola hepatica infections were performed with recombinant Sm14 (rSm14) produced in Escherichia coli by the pGEMEX system (Promega). The rSm14 was expressed as a 40 kDa fusion protein with the major bacteriophage T7 capsid protein. Vaccination experiments with this rSm14 in animal models resulted...

Scorpion Venom Pisoning in Experimental Animals

Asbestosis in experimental animals.

Previous animal experiments with asbestos dusts have been almost entirely confined to chrysotile asbestos. It was, therefore, decided to investigate the effects of mill dusts from the three types of asbestos that are produced commercially in South Africa, namely chrysotile, amosite, and crocidolite. Chrysotile and amosite samples were relatively pure while in contrast the crocidolite dust was f...

Fasting and Experimental Animals, Detrimental or Positive?

While fasting has been practiced for centuries, its beneficial effects was unknown until recently. This review tries to analyze the current literature of how fasting and intermittent fasting (IF) could affect clinical pathological parameters, learning, mood and brain plasticity. The effects of different ways of fasting on metabolism and stress were also explored. Animal experiments have elucida...

Sepsis Models in Experimental Animals

Sepsis develops as a common inflammatory response to various infections. It runs with the picture of a complex heterogeneous syndrome which often leads to the development of multiple organ dysfunctions and causes the death of millions of people worldwide. For various reasons, detailed research of sepsis in humans is difficult to conduct; therefore, a lot of efforts have been made to model it. P...